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Structures of 2-Acetylaminofluorene Modified DNA Revisited: Insight into Conformational Heterogeneity

Despite the extensive data on dG-AAF, the major DNA adduct derived from the model carcinogen 2-acetylaminofluorene, little is known with respect to its solution structures. Here we provide NMR/CD evidence for three conformers of dG-AAF in duplex DNA: major groove (B), base-displaced stacked (S), and...

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Bibliografski detalji
Glavni autori: Patnaik, Satyakam, Cho, Bongsup P.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981646/
https://ncbi.nlm.nih.gov/pubmed/20954689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100341u
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