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Structures of 2-Acetylaminofluorene Modified DNA Revisited: Insight into Conformational Heterogeneity
Despite the extensive data on dG-AAF, the major DNA adduct derived from the model carcinogen 2-acetylaminofluorene, little is known with respect to its solution structures. Here we provide NMR/CD evidence for three conformers of dG-AAF in duplex DNA: major groove (B), base-displaced stacked (S), and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981646/ https://ncbi.nlm.nih.gov/pubmed/20954689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100341u |
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