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Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.

Eukaryotic translation initiation factor-4A (eIF-4A) plays a critical role in binding of eukaryotic mRNAs to ribosomes. It has been biochemically characterized as an RNA-dependent ATPase and RNA helicase and is a prototype for a growing family of putative RNA helicases termed the DEAD box family. It...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Pause, A, Méthot, N, Svitkin, Y, Merrick, W C, Sonenberg, N
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1994
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC394930/
https://ncbi.nlm.nih.gov/pubmed/8131750
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