Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A.

Por Pause, A, Sonenberg, N
Publicado em 1992

The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis.

Por Pause, A, Méthot, N, Sonenberg, N
Publicado em 1993

The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins.

Por Mader, S, Lee, H, Pause, A, Sonenberg, N
Publicado em 1995

La autoantigen alleviates translational repression by the 5' leader sequence of the human immunodeficiency virus type 1 mRNA.

Por Svitkin, Y V, Pause, A, Sonenberg, N
Publicado em 1994

Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E.

Por Haghighat, A, Mader, S, Pause, A, Sonenberg, N
Publicado em 1995

The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence.

Por Méthot, N, Pause, A, Hershey, J W, Sonenberg, N
Publicado em 1994

Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.

Por Pause, A, Méthot, N, Svitkin, Y, Merrick, W C, Sonenberg, N
Publicado em 1994

Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

Por Gingras, A C, Svitkin, Y, Belsham, G J, Pause, A, Sonenberg, N
Publicado em 1996

ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae.

Por Blum, S, Schmid, S R, Pause, A, Buser, P, Linder, P, Sonenberg, N, Trachsel, H
Publicado em 1992

The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

Por Svitkin, Y V, Pause, A, Haghighat, A, Pyronnet, S, Witherell, G, Belsham, G J, Sonenberg, N
Publicado em 2001

Absence of the Birt–Hogg–Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

Por Preston, RS, Philp, A, Claessens, T, Gijezen, L, Dydensborg, AB, Dunlop, EA, Harper, KT, Brinkhuizen, T, Menko, FH, Davies, DM, Land, SC, Pause, A, Baar, K, van Steensel, MAM, Tee, AR
Publicado em 2010