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The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis.

eIF-4A is a eukaryotic translation initiation factor that is required for mRNA binding to ribosomes. It exhibits single-stranded RNA-dependent ATPase activity, and in combination with a second initiation factor, eIF-4B, it exhibits duplex RNA helicase activity. eIF-4A is the prototype of a large fam...

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Bibliografiska uppgifter
Huvudupphovsmän: Pause, A, Méthot, N, Sonenberg, N
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1993
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC364741/
https://ncbi.nlm.nih.gov/pubmed/8413273
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