The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis.

eIF-4A is a eukaryotic translation initiation factor that is required for mRNA binding to ribosomes. It exhibits single-stranded RNA-dependent ATPase activity, and in combination with a second initiation factor, eIF-4B, it exhibits duplex RNA helicase activity. eIF-4A is the prototype of a large fam...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Pause, A, Méthot, N, Sonenberg, N
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413273/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6789-6798.1993
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