The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis.
eIF-4A is a eukaryotic translation initiation factor that is required for mRNA binding to ribosomes. It exhibits single-stranded RNA-dependent ATPase activity, and in combination with a second initiation factor, eIF-4B, it exhibits duplex RNA helicase activity. eIF-4A is the prototype of a large fam...
Enregistré dans:
| Publié dans: | Mol Cell Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
1993
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413273/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.11.6789-6798.1993 |
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