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Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation.

Eukaryotic translation initiation factor-4A (eIF-4A) plays a critical role in binding of eukaryotic mRNAs to ribosomes. It has been biochemically characterized as an RNA-dependent ATPase and RNA helicase and is a prototype for a growing family of putative RNA helicases termed the DEAD box family. It...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Pause, A, Méthot, N, Svitkin, Y, Merrick, W C, Sonenberg, N
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394930/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8131750/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06370.x
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