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BCL::Fold – Protein topology determination from limited NMR restraints

When experimental protein NMR data is too sparse to apply traditional structure determination techniques, de novo protein structure prediction methods can be leveraged. Here we describe the incorporation of NMR restraints into the protein structure prediction algorithm BCL::Fold. The method assemble...

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Bibliographic Details
Main Authors: Weiner, Brian E., Alexander, Nathan, Akin, Louesa R., Woetzel, Nils, Karakas, Mert, Meiler, Jens
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949166/
https://ncbi.nlm.nih.gov/pubmed/24123100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24427
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