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BCL::Fold – Protein topology determination from limited NMR restraints

When experimental protein NMR data is too sparse to apply traditional structure determination techniques, de novo protein structure prediction methods can be leveraged. Here we describe the incorporation of NMR restraints into the protein structure prediction algorithm BCL::Fold. The method assemble...

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Detalhes bibliográficos
Main Authors: Weiner, Brian E., Alexander, Nathan, Akin, Louesa R., Woetzel, Nils, Karakas, Mert, Meiler, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949166/
https://ncbi.nlm.nih.gov/pubmed/24123100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24427
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