A Phase I Study of Intermittently Dosed Vorinostat in Combination with Bortezomib in Patients with Advanced Solid Tumors

BACKGROUND: Accumulating evidence shows evidence of efficacy with the combination of vorinostat and bortezomib in solid tumors. We previously examined a once-daily continuous dosing schedule of vorinostat in combination with bortezomib which was well tolerated in cycles 1 and 2; however, there was c...

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Main Authors: Deming, Dustin A., Ninan, Jacob, Bailey, Howard H., Kolesar, Jill M., Eickhoff, Jens, Reid, Joel, Ames, Matthew M., McGovern, Renee M., Alberti, Dona, Marnocha, Rebecca, Espinoza-Delgado, Igor, Wright, John, Wilding, George, Schelman, William R.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949160/
https://ncbi.nlm.nih.gov/pubmed/24114123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-0035-8
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