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Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart
In vitro studies suggested that glucose metabolism through the oxidative pentose phosphate pathway (oxPPP) can paradoxically feed superoxide-generating enzymes in failing hearts. We therefore tested the hypothesis that acute inhibition of the oxPPP reduces oxidative stress and enhances function and...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949072/ https://ncbi.nlm.nih.gov/pubmed/24414069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00783.2013 |
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