The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization

Diabetes mellitus increases the risk for cardiac dysfunction, heart failure, and sudden death. The wide array of neurohumoral changes associated with diabetes pose a challenge to understanding the roles of specific pathways that alter cardiac function. Here, we use a mouse model with cardiomyocyte-r...

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Autori principali: Lopez-Izquierdo, Angelica, Pereira, Renata O., Wende, Adam R., Punske, Bonnie B., Abel, E. Dale, Tristani-Firouzi, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
Soggetti:
Cardiac Excitation and Contraction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949065/
https://ncbi.nlm.nih.gov/pubmed/24375641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00849.2013
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