The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization

Diabetes mellitus increases the risk for cardiac dysfunction, heart failure, and sudden death. The wide array of neurohumoral changes associated with diabetes pose a challenge to understanding the roles of specific pathways that alter cardiac function. Here, we use a mouse model with cardiomyocyte-r...

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Bibliographic Details
Main Authors: Lopez-Izquierdo, Angelica, Pereira, Renata O., Wende, Adam R., Punske, Bonnie B., Abel, E. Dale, Tristani-Firouzi, Martin
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
Subjects:
Cardiac Excitation and Contraction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949065/
https://ncbi.nlm.nih.gov/pubmed/24375641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00849.2013
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