Pulmonary vasoconstrictor influence of endothelin in exercising swine depends critically on phosphodiesterase 5 activity

Both phosphodiesterase 5 (PDE5) inhibition and endothelin (ET) receptor blockade have been shown to induce pulmonary vasodilation. However, little is known about the effect of combined blockade of these two vasoconstrictor pathways. Since nitric oxide (NO) exerts its pulmonary vasodilator influence...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhou, Zhichao, de Beer, Vincent J., de Wijs-Meijler, Daphne, Bender, Shawn B., Hoekstra, Maaike, Laughlin, M. Harold, Duncker, Dirk J., Merkus, Daphne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2014
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949058/
https://ncbi.nlm.nih.gov/pubmed/24414253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00057.2013
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