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Insulin treatment attenuates renal ADAM17 and ACE2 shedding in diabetic Akita mice
Angiotensin-converting enzyme 2 (ACE2) is located in several tissues and is highly expressed in renal proximal tubules, where it degrades the vasoconstrictor angiotensin II (ANG II) to ANG-(1–7). Accumulating evidence supports protective roles of ACE2 in several disease states, including diabetic ne...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949038/ https://ncbi.nlm.nih.gov/pubmed/24452639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00516.2013 |
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