Insulin treatment attenuates renal ADAM17 and ACE2 shedding in diabetic Akita mice

Angiotensin-converting enzyme 2 (ACE2) is located in several tissues and is highly expressed in renal proximal tubules, where it degrades the vasoconstrictor angiotensin II (ANG II) to ANG-(1–7). Accumulating evidence supports protective roles of ACE2 in several disease states, including diabetic ne...

Full description

Saved in:
Bibliographic Details
Main Authors: Salem, Esam S. B., Grobe, Nadja, Elased, Khalid M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949038/
https://ncbi.nlm.nih.gov/pubmed/24452639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00516.2013
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items