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Functional and molecular evidence for expression of the renin angiotensin system and ADAM17-mediated ACE2 shedding in COS7 cells

The renin angiotensin system (RAS) plays a vital role in the regulation of the cardiovascular and renal functions. COS7 is a robust and easily transfectable cell line derived from the kidney of the African green monkey, Cercopithecus aethiops. The aims of this study were to 1) demonstrate the presen...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Grobe, Nadja, Di Fulvio, Mauricio, Kashkari, Nada, Chodavarapu, Harshita, Somineni, Hari K., Singh, Richa, Elased, Khalid M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420792/
https://ncbi.nlm.nih.gov/pubmed/25740155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00247.2014
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