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Intracellular signalling mechanism responsible for modulation of sarcolemmal ATP-sensitive potassium channels by nitric oxide in ventricular cardiomyocytes

The ATP-sensitive potassium (K(ATP)) channels are crucial for stress adaptation in the heart. It has previously been suggested that the function of K(ATP) channels is modulated by nitric oxide (NO), a gaseous messenger known to be cytoprotective; however, the underlying mechanism remains poorly unde...

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Autors principals: Zhang, Dai-Min, Chai, Yongping, Erickson, Jeffrey R, Brown, Joan Heller, Bers, Donald M, Lin, Yu-Fung
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948558/
https://ncbi.nlm.nih.gov/pubmed/24277866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.264697
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