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Disruption of Sarcolemmal ATP sensitive potassium Channel Activity Impairs the Cardiac Response to Systolic Overload

Sarcolemmal ATP sensitive potassium Channels (K(ATP)) act as metabolic sensors that facilitate adaptation of the left ventricle (LV) to changes in energy requirements. This study examined the mechanism by which K(ATP) dysfunction impairs the LV response to stress using transgenic mouse strains with...

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Autori principali: Hu, Xinli, Xu, Xin, Huang, Yimin, Fassett, John, Flagg, Thomas P., Zhang, Ying, Nichols, Colin G., Bache, Robert J., Chen, Yingjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877276/
https://ncbi.nlm.nih.gov/pubmed/18802029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.170795
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