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Activation of cGMP-Dependent Protein Kinase Stimulates Cardiac ATP-Sensitive Potassium Channels via a ROS/Calmodulin/CaMKII Signaling Cascade

BACKGROUND: Cyclic GMP (cGMP)-dependent protein kinase (PKG) is recognized as an important signaling component in diverse cell types. PKG may influence the function of cardiac ATP-sensitive potassium (K(ATP)) channels, an ion channel critical for stress adaptation in the heart; however, the underlyi...

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Detalhes bibliográficos
Main Authors: Chai, Yongping, Zhang, Dai-Min, Lin, Yu-Fung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066208/
https://ncbi.nlm.nih.gov/pubmed/21479273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018191
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