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Ouabain–digoxin antagonism in rat arteries and neurones

KEY POINTS: ‘Classic’ cardiotonic steroids (CTSs) all inhibit Na(+),K(+)‐ATPase (Na(+) pumps) and exert cardiotonic and vasotonic effects. Nevertheless, prolonged ouabain, but not digoxin, administration induces hypertension; moreover, digoxin antagonizes the hypertensinogenic effect of ouabain. To...

詳細記述

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書誌詳細
主要な著者: Song, Hong, Karashima, Eiji, Hamlyn, John M., Blaustein, Mordecai P.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948557/
https://ncbi.nlm.nih.gov/pubmed/24344167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.266866
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