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Ouabain–digoxin antagonism in rat arteries and neurones
KEY POINTS: ‘Classic’ cardiotonic steroids (CTSs) all inhibit Na(+),K(+)‐ATPase (Na(+) pumps) and exert cardiotonic and vasotonic effects. Nevertheless, prolonged ouabain, but not digoxin, administration induces hypertension; moreover, digoxin antagonizes the hypertensinogenic effect of ouabain. To...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948557/ https://ncbi.nlm.nih.gov/pubmed/24344167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.266866 |
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