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Signaling Mechanisms that Link Salt Retention to Hypertension: Endogenous Ouabain, the Na(+) Pump, the Na(+)/Ca(2+) Exchanger and TRPC Proteins

Salt retention as a result of chronic, excessive dietary salt intake, is widely accepted as one of the most common causes of hypertension. In a small minority of cases, enhanced Na(+) reabsorption by the kidney can be traced to specific genetic defects of salt transport, or pathological conditions o...

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Detalhes bibliográficos
Main Authors: Blaustein, Mordecai P., Hamlyn, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909369/
https://ncbi.nlm.nih.gov/pubmed/20211726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.02.011
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