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Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission

Microglia are highly sensitive to even small changes in the brain environment, such as invasion of non-hazardous toxicants or the presymptomatic state of diseases. However, the physiological or pathophysiological consequences of their responses remain unknown. Here, we report that cultured microglia...

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Detalhes bibliográficos
Main Authors: Shinozaki, Youichi, Nomura, Masatoshi, Iwatsuki, Ken, Moriyama, Yoshinori, Gachet, Christian, Koizumi, Schuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948352/
https://ncbi.nlm.nih.gov/pubmed/24710318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04329
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