Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes

Although psychotropic drugs act on neurons and glial cells, how glia respond, and whether glial responses are involved in therapeutic effects are poorly understood. Here, we show that fluoxetine (FLX), an anti-depressant, mediates its anti-depressive effect by increasing the gliotransmission of ATP....

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Foilsithe in:EBioMedicine
Main Authors: Kinoshita, Manao, Hirayama, Yuri, Fujishita, Kayoko, Shibata, Keisuke, Shinozaki, Youichi, Shigetomi, Eiji, Takeda, Akiko, Le, Ha Pham Ngoc, Hayashi, Hideaki, Hiasa, Miki, Moriyama, Yoshinori, Ikenaka, Kazuhiro, Tanaka, Kenji F., Koizumi, Schuichi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2018
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020856/
https://ncbi.nlm.nih.gov/pubmed/29887330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.05.036
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