Anti-Depressant Fluoxetine Reveals its Therapeutic Effect Via Astrocytes

Although psychotropic drugs act on neurons and glial cells, how glia respond, and whether glial responses are involved in therapeutic effects are poorly understood. Here, we show that fluoxetine (FLX), an anti-depressant, mediates its anti-depressive effect by increasing the gliotransmission of ATP....

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Kinoshita, Manao, Hirayama, Yuri, Fujishita, Kayoko, Shibata, Keisuke, Shinozaki, Youichi, Shigetomi, Eiji, Takeda, Akiko, Le, Ha Pham Ngoc, Hayashi, Hideaki, Hiasa, Miki, Moriyama, Yoshinori, Ikenaka, Kazuhiro, Tanaka, Kenji F., Koizumi, Schuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6020856/
https://ncbi.nlm.nih.gov/pubmed/29887330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.05.036
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