Reactive astrocyte-driven epileptogenesis is induced by microglia initially activated following status epilepticus

Extensive activation of glial cells during a latent period has been well documented in various animal models of epilepsy. However, it remains unclear whether activated glial cells contribute to epileptogenesis, i.e., the chronically persistent process leading to epilepsy. Particularly, it is not cle...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Sano, Fumikazu, Shigetomi, Eiji, Shinozaki, Youichi, Tsuzukiyama, Haruka, Saito, Kozo, Mikoshiba, Katsuhiko, Horiuchi, Hiroshi, Cheung, Dennis Lawrence, Nabekura, Junichi, Sugita, Kanji, Aihara, Masao, Koizumi, Schuichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262323/
https://ncbi.nlm.nih.gov/pubmed/33830944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135391
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