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Dynamic look at DNA unwinding by a replicative helicase

A prerequisite for DNA replication is the unwinding of duplex DNA catalyzed by a replicative hexameric helicase. Despite a growing body of research, key elements of helicase mechanism remain under substantial debate. In particular, the number of DNA strands encircled by the helicase ring during unwi...

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Autors principals: Lee, Seung-Jae, Syed, Salman, Enemark, Eric J., Schuck, Stephen, Stenlund, Arne, Ha, Taekjip, Joshua-Tor, Leemor
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948270/
https://ncbi.nlm.nih.gov/pubmed/24550505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322254111
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