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Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration

Cone phototransduction and survival of cones in the human macula is essential for color vision and for visual acuity. Progressive cone degeneration in age-related macular degeneration, Stargardt disease, and recessive cone dystrophies is a major cause of blindness. Thyroid hormone (TH) signaling, wh...

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Detalhes bibliográficos
Main Authors: Ma, Hongwei, Thapa, Arjun, Morris, Lynsie, Redmond, T. Michael, Baehr, Wolfgang, Ding, Xi-Qin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948228/
https://ncbi.nlm.nih.gov/pubmed/24550448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317041111
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