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Regulation of human telomerase splicing by RNA:RNA pairing
Telomerase adds telomeric repeats onto chromosome ends and is almost universally upregulated in human cancers. Here we demonstrate that RNA:RNA pairing regulates splicing of the catalytic subunit of human telomerase (TERT). Human alleles contain a variable number of 38 bp repeats within TERT intron...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Pub. Group
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948165/ https://ncbi.nlm.nih.gov/pubmed/24577044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4306 |
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