Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.

Intraerythrocytic malaria parasites rapidly degrade virtually all of the host cell hemoglobin. We have cloned the gene for an aspartic hemoglobinase that initiates the hemoglobin degradation pathway in Plasmodium falciparum. It encodes a protein with 35% homology to human renin and cathepsin D, but...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Francis, S E, Gluzman, I Y, Oksman, A, Knickerbocker, A, Mueller, R, Bryant, M L, Sherman, D R, Russell, D G, Goldberg, D E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC394809/
https://ncbi.nlm.nih.gov/pubmed/8313875
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