Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.

Plasmodium falciparum is the major causative agent of malaria, a disease of worldwide importance. Resistance to current drugs such as chloroquine and mefloquine is spreading at an alarming rate, and our antimalarial armamentarium is almost depleted. The malarial parasite encodes two homologous aspar...

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Detalhes bibliográficos
Main Authors: Silva, A M, Lee, A Y, Gulnik, S V, Maier, P, Collins, J, Bhat, T N, Collins, P J, Cachau, R E, Luker, K E, Gluzman, I Y, Francis, S E, Oksman, A, Goldberg, D E, Erickson, J W
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC38331/
https://ncbi.nlm.nih.gov/pubmed/8816746
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