Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.

Plasmodium falciparum is the major causative agent of malaria, a disease of worldwide importance. Resistance to current drugs such as chloroquine and mefloquine is spreading at an alarming rate, and our antimalarial armamentarium is almost depleted. The malarial parasite encodes two homologous aspar...

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में प्रकाशित:	Proc Natl Acad Sci U S A
मुख्य लेखकों:	Silva, A M, Lee, A Y, Gulnik, S V, Maier, P, Collins, J, Bhat, T N, Collins, P J, Cachau, R E, Luker, K E, Gluzman, I Y, Francis, S E, Oksman, A, Goldberg, D E, Erickson, J W
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	National Academy of Sciences 1996
विषय:	Research Article
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38331/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816746/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.19.10034
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