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Targeting Gli Transcription Activation by Small Molecule Suppresses Tumor Growth
Targeted inhibition of Hedgehog signaling at the cell membrane has been associated with anti-cancer activity in preclinical and early clinical studies. Hedgehog signaling involves activation of Gli transcription factors that can also be induced by alternative pathways. In this study we identified an...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947751/ https://ncbi.nlm.nih.gov/pubmed/23686308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.164 |
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