Testing the anti-fibrotic potential of the single-chain Fv antibody against the α2 C-terminal telopeptide of collagen I

This study focuses on the single chain fragment variable (scFv) variant of the original IgA-type antibody, recognizing the α2 C-terminal telopeptide (α2Ct) of human collagen I, designed to inhibit post-traumatic localized fibrosis via blocking the formation of collagen-rich deposits. We have demonst...

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Autori principali: Fertala, Jolanta, Kostas, James, Hou, Cheryl, Steplewski, Andrzej, Beredjiklian, Pedro, Abboud, Joseph, Arnold, William V., Williams, Gerald, Fertala, Andrzej
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947660/
https://ncbi.nlm.nih.gov/pubmed/24195607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2013.862528
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