Engineering and Characterization of the Chimeric Antibody that Targets the C-terminal Telopeptide of the α2 Chain of Human Collagen I: A Next Step in the Quest to Reduce Localized Fibrosis

Inhibition of the extracellular process of collagen fibril formation represents a new approach to limiting posttraumatic or postsurgical localized fibrosis. It has been demonstrated that employing a monoclonal antibody that targets the C-terminal telopeptide of the α2 chain of collagen I blocks crit...

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Main Authors: Fertala, Jolanta, Steplewski, Andrzej, Kostas, James, Beredjiklian, Pedro, Williams, Gerard, Arnold, William, Abboud, Joseph, Bhardwaj, Anshul, Hou, Cheryl, Fertala, Andrzej
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896972/
https://ncbi.nlm.nih.gov/pubmed/23586407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03008207.2013.778839
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