Prospects and limitations of improving skeletal growth in a mouse model of spondyloepiphyseal dysplasia caused by R992C (p.R1192C) substitution in collagen II

Skeletal dysplasias form a group of skeletal disorders caused by mutations in macromolecules of cartilage and bone. The severity of skeletal dysplasias ranges from precocious arthropathy to perinatal lethality. Although the pathomechanisms of these disorders are generally well defined, the feasibili...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Arita, Machiko, Fertala, Jolanta, Hou, Cheryl, Kostas, James, Steplewski, Andrzej, Fertala, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300241/
https://ncbi.nlm.nih.gov/pubmed/28182776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172068
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