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Prospects and limitations of improving skeletal growth in a mouse model of spondyloepiphyseal dysplasia caused by R992C (p.R1192C) substitution in collagen II

Skeletal dysplasias form a group of skeletal disorders caused by mutations in macromolecules of cartilage and bone. The severity of skeletal dysplasias ranges from precocious arthropathy to perinatal lethality. Although the pathomechanisms of these disorders are generally well defined, the feasibili...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Arita, Machiko, Fertala, Jolanta, Hou, Cheryl, Kostas, James, Steplewski, Andrzej, Fertala, Andrzej
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300241/
https://ncbi.nlm.nih.gov/pubmed/28182776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172068
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