In vivo metabolic flux profiling with stable isotopes discriminates sites and quantifies effects of mitochondrial dysfunction in C. elegans

Mitochondrial respiratory chain (RC) disease diagnosis is complicated both by an absence of biomarkers that sufficiently divulge all cases and limited capacity to quantify adverse effects across intermediary metabolism. We applied high performance liquid chromatography (HPLC) and mass spectrometry (...

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Detaylı Bibliyografya
Asıl Yazarlar: Vergano, Samantha Schrier, Rao, Meera, McCormack, Shana, Ostrovsky, Julian, Clarke, Colleen, Preston, Judith, Bennett, Michael J., Yudkoff, Marc, Xiao, Rui, Falk, Marni J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947636/
https://ncbi.nlm.nih.gov/pubmed/24445252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2013.12.011
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