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Analysis of a glucocorticoid-estrogen receptor chimera reveals that dimerization energetics are under ionic control

Steroid receptors assemble at DNA response elements as dimers, resulting in coactivator recruitment and transcriptional activation. Our work has focused on dissecting the energetics associated with these events and quantitatively correlating the results with function. A recent finding is that differ...

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Detalles Bibliográficos
Autores principales: Connaghan, Keith D., Miura, Michael T., Maluf, Nasib K., Lambert, James R., Bain, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947562/
https://ncbi.nlm.nih.gov/pubmed/23333595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2012.12.005
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