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Analysis of a glucocorticoid-estrogen receptor chimera reveals that dimerization energetics are under ionic control

Steroid receptors assemble at DNA response elements as dimers, resulting in coactivator recruitment and transcriptional activation. Our work has focused on dissecting the energetics associated with these events and quantitatively correlating the results with function. A recent finding is that differ...

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Detalhes bibliográficos
Main Authors: Connaghan, Keith D., Miura, Michael T., Maluf, Nasib K., Lambert, James R., Bain, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947562/
https://ncbi.nlm.nih.gov/pubmed/23333595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2012.12.005
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