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Thermodynamic analysis of progesterone receptor–promoter interactions reveals a molecular model for isoform-specific function
Human progesterone receptors (PR) exist as two functionally distinct isoforms, PR-A and PR-B. The proteins are identical except for an additional 164 residues located at the N terminus of PR-B. To determine the mechanisms responsible for isoform-specific functional differences, we present here a the...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892943/ https://ncbi.nlm.nih.gov/pubmed/17277083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608848104 |
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