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Cooperative DNA Binding by the B-Isoform of Human Progesterone Receptor: Thermodynamic Analysis Reveals Strongly Favorable and Unfavorable Contributions to Assembly

Progesterone receptors (PR) play critical roles in eukaryotic gene regulation, yet the mechanisms by which they assemble at multi-site promoters are poorly understood. Here we present a thermodynamic analysis of the interactions of the PR B-isoform (PR-B) with promoters containing either one or two...

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Autori principali: Heneghan, Aaron F., Connaghan-Jones, Keith D., Miura, Michael T., Bain, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505112/
https://ncbi.nlm.nih.gov/pubmed/16519523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052046g
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