Factors Associated with Variability in Rifampin Plasma Pharmacokinetics and the Relationship between Rifampin Concentrations and Induction of Efavirenz Clearance

STUDY OBJECTIVES: To identify factors associated with variability in rifampin plasma pharmacokinetics and explore the relationship between rifampin pharmacokinetics and change in efavirenz plasma pharmacokinetics with rifampin coadministration. METHODS: In this randomized, cross-over study, 12 healt...

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Auteurs principaux: Kwara, Awewura, Cao, Lei, Yang, Hongmei, Poethke, Pamela, Kurpewski, Jaclynn, Tashima, Karen T., Mahjoub, Behrang D., Court, Michael H., Peloquin, Charles A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947488/
https://ncbi.nlm.nih.gov/pubmed/24420746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phar.1388
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