Microfluidic assay of hemophilic blood clotting: Distinct deficits in platelet and fibrin deposition at low factor levels

BACKGROUND: Coagulation factor deficiencies create a range of bleeding phenotypes. Microfluidic devices offer controlled hemodynamics and defined procoagulant triggers for measurement of clotting under flow. OBJECTIVES: We tested a flow assay of contact pathway-triggered clotting to quantify platele...

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Hauptverfasser: Colace, T., Fogarty, Patrick F., Panckeri, Karen A., Li, Ruizhi, Diamond, S.L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947474/
https://ncbi.nlm.nih.gov/pubmed/24261634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12457
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