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Microfluidic assay of hemophilic blood clotting: Distinct deficits in platelet and fibrin deposition at low factor levels
BACKGROUND: Coagulation factor deficiencies create a range of bleeding phenotypes. Microfluidic devices offer controlled hemodynamics and defined procoagulant triggers for measurement of clotting under flow. OBJECTIVES: We tested a flow assay of contact pathway-triggered clotting to quantify platele...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947474/ https://ncbi.nlm.nih.gov/pubmed/24261634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12457 |
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