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Immunoglobulin gene transcription ceases upon deletion of a distant enhancer.

The tissue-specific E mu enhancer within the immunoglobulin heavy chain (IgH) locus has recently been shown to be essential for efficient V region gene assembly in early B lineage cells. However, we and others have shown that late stage, Ig-secreting cells can produce IgH in the absence of E mu. In...

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書誌詳細
主要な著者: Lieberson, R, Ong, J, Shi, X, Eckhardt, L A
フォーマット: Artigo
言語:Inglês
出版事項: 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC394747/
https://ncbi.nlm.nih.gov/pubmed/8557042
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