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Deletion of a B-cell-specific enhancer affects transfected, but not endogenous, immunoglobulin heavy-chain gene expression.

A transcriptional enhancer has recently been identified between the variable and constant region coding segments of an assembled immunoglobulin heavy-chain gene. This enhancer is required for efficient expression of such genes when transfected into myeloma cells. A class switch rearrangement in the...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Zaller, D M, Eckhardt, L A
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1985
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390504/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3927296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.15.5088
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