Deletion of a B-cell-specific enhancer affects transfected, but not endogenous, immunoglobulin heavy-chain gene expression.
A transcriptional enhancer has recently been identified between the variable and constant region coding segments of an assembled immunoglobulin heavy-chain gene. This enhancer is required for efficient expression of such genes when transfected into myeloma cells. A class switch rearrangement in the...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1985
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3927296/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.15.5088 |
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