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Nonparametric modeling and analysis of association between Huntington’s disease onset and CAG repeats

Huntington’s disease (HD) is a neurodegenerative disorder with a dominant genetic mode of inheritance caused by an expansion of CAG repeats on chromosome 4. Typically, a longer sequence of CAG repeat length is associated with increased risk of experiencing earlier onset of HD. Previous studies of th...

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Détails bibliographiques
Auteurs principaux: Ma, Yanyuan, Wang, Yuanjia
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947445/
https://ncbi.nlm.nih.gov/pubmed/24027120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5971
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