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Amyloid-β Deposits Lead to Retinal Degeneration in a Mouse Model of Alzheimer Disease

PURPOSE: To compare the temporal and spatial expression patterns of amyloid precursor protein (APP), amyloid-β deposits, inflammatory chemokines, and apoptosis in the retina of a mouse model of Alzheimer disease (AD). METHODS: Retinas of transgenic mice harboring a mutant presenilin (PS1) and a muta...

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Sonraí Bibleagrafaíochta
Main Authors: Ning, Allison, Cui, Jing, To, Eleanor, Ashe, Karen Hsiao, Matsubara, Joanne
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947384/
https://ncbi.nlm.nih.gov/pubmed/18566467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-1849
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