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Amyloid-β Deposits Lead to Retinal Degeneration in a Mouse Model of Alzheimer Disease
PURPOSE: To compare the temporal and spatial expression patterns of amyloid precursor protein (APP), amyloid-β deposits, inflammatory chemokines, and apoptosis in the retina of a mouse model of Alzheimer disease (AD). METHODS: Retinas of transgenic mice harboring a mutant presenilin (PS1) and a muta...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947384/ https://ncbi.nlm.nih.gov/pubmed/18566467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-1849 |
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